“Illuminoz talks 2025” podcast series
Multiple Sclerosis

Episode 12 – PML: what is it, and why is it relevant in MS?

dr Tobias Bopp
dr Tobias Bopp

01 września 2025

In the final episode of the Illuminoz podcast series, Bianca Stadler speaks with Dr. Tobias Bopp – immunologist and director of the Institute of Immunology in Mainz – about the risk of progressive multifocal leukoencephalopathy (PML) in MS treatment and the role of JC virus testing.

What immune mechanisms protect against PML? What are the key risk factors when using natalizumab? And how does JCV antibody testing support safer treatment decisions?

This episode highlights the importance of safety, biomarkers, and personalized care in the evolving landscape of MS therapy.